RE: Fixed elements within a block covariance matrix
From: Vladimir Piotrovsky, Ph.D. - VPIOTROV@PRDBE.jnj.com
Subject: RE: [NMusers] Fixed elements within a block covariance matrix
Date: 1/13/2004 9:27 AM
Pete,
You can try to change the indices of ETAs to come up with the matrix
[X11
X21 X22
0 X32 X33]
In this case you can fix the lower left element to zero.
Best regards,
Vladimir
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Vladimir Piotrovsky, Ph.D.
Research Fellow, Advanced PK-PD Modeling & Simulation
Global Clinical Pharmacokinetics and Clinical Pharmacology (ext. 5463/151)
Johnson & Johnson Pharmaceutical Research & Development
Turnhoutseweg 30
B-2340 Beerse
Belgium