Re: Scaling of pharmacokinetics in peds
From: Jenny Yuehling Chien - CHIEN_JENNY_YUEHLING@lilly.com
Subject: Re: [NMusers] Scaling of pharmacokinetics in peds
Date: 12/23/2003 3:57 PM
Nick,
There are 2 papers on phenytoin, Ted can probably verify that:
- steady-state pharmacokinetics of phenytoin from routinelycollected patient data.
Clinical Pharmacokinetics. 8(4):355-64, 1983.
- phenytoin pharmacokinetics: inappropriate data analysis.
American Journal of Hospital Pharmacy. 39(1):41-3, 1982
You must be thinking of the first paper with an age effect on Km.
jenny
Jenny Chien, PhD
research scientist
Global PK/PD & TS
Lilly Research Laboratories
Lilly Corporate Center
Indianapolis, IN 46285
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