RE: ERROR: ABSORPTION LAG IS GREATER THAN OR EQUAL TO STEADY STATE DOSE INTERVAL

From: William Bachman Date: December 23, 2003 technical Source: cognigencorp.com
From: "Bachman, William (MYD)" - bachmanw@iconus.com Subject: RE: [NMusers] ERROR: ABSORPTION LAG IS GREATER THAN OR EQUAL TO STEADY STATE DOSE INTERVAL Date: 12/23/2003 9:15 AM David, Just an empirical suggestion (I haven't really thoroughly looked over your control stream and data snippet), but, I would try using an additive variance model on the ALAG1 (and possibly the KA, as well). In my experience, they tend not to be log normally distributed. Bill William J. Bachman, Ph.D. Manager, Pharmacometrics Research and Development GloboMax The Strategic Pharmaceutical Development Division of ICON plc 7250 Parkway Drive, Suite 430 Hanover, MD 21076 410-782-2212 bachmanw@iconus.com

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Dec 23, 2003 David Foster ERROR: ABSORPTION LAG IS GREATER THAN OR EQUAL TO STEADY STATE DOSE INTERVAL
Dec 23, 2003 William Bachman RE: ERROR: ABSORPTION LAG IS GREATER THAN OR EQUAL TO STEADY STATE DOSE INTERVAL
Jan 06, 2004 Vladimir Piotrovskij RE: ERROR: ABSORPTION LAG IS GREATER THAN OR EQUAL TO STEADY STATE DOSE INTERVAL
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