Re: Nonmem model

From: Batul Parta - batulparta@yahoo.com Subject: Re: [NMusers] Nonmem model Date: 12/19/2003 10:04 AM Thank you for the suggestions. I entered the first observation as dose and the model converges, estimating parameters. However, I am uncertain if the procedure is correct. If the observations are given as log-transformed data in the data file, what does nonmem add up, when adding the contents of the 2 compartments? Obviously, one needs to add the non-transformed DV. Does nonmem read the data file, converts the log-transformed data in the data file to non-transformed, adds them, and then transfers back to the log scale? Should I try entering the data as observed (not log-transformed) in the data file or is there any other way to make nonmem do the correct adding? Once again, thank you for you help! B. Part