RE: How to do simulation?

From: "Bachman, William (MYD)" bachmanw@iconus.com Subject: RE: [NMusers] How to do simulation? Date: 11/6/2003 3:08 PM Write the compartmental model that represent the plausible biological model including the parent and metabolite (using general linear models or differential equation defined model). Create a data file containing the dose records, the observation records for the parent and observation records for the metabolite (in chronological order of course). Include the CMT and EVID data items. Dose records will be CMT=# of compartment where dosed and EVID=0, parent observation records will have CMT=# of compartment where parent is observed and EVID=1, and the metabolite records will have CMT=# of compartment where metabolite is observed and EVID=1. If there are times that you would like predictions that you don't have observations, insert records with the appropriate CMT (for parent or metabolite) and EVID=2. The prediction is always the prediction for the appropriate CMT if it is coded, otherwise the PRED defaults are used. Is this what you are asking?