RE: large CV

From:"Sam Liao" Subject: RE: [NMusers] large CV Date:Wed, 5 Mar 2003 09:25:42 -0500 Dear Luciane: two more possibilities, 1) You don't have initial estimates in theta and omega for KA. 2) It may be quite possible that it converge to a local minimum. How is the diagnostic plots look like? In my experience, the inital estimates for two-compartment model are very critical. Best regards, Sam Liao, Ph.D. PharMax Research PO Box 1809, 20 Second Street, Jersey City, NJ 07302 phone: 201-7983202 efax: 1-720-2946783