Re: Wrong model
From: "Sambol, Nancy"
Subject:Re: [NMusers] Wrong model
Date:Fri, 12 Jul 2002 10:52:24 -0700
Hi Peter and Nonmem users,
The impact of structural model misspecification on other parts of the model was
addressed in the following paper. A bit of a surprise for us (at least then) was that
the impact of the misspecification also depends on your statistical model
(whether parameters are allowed to covary or not).
Wade JR, Beal SL and Sambol NC. Interaction between structural, statistical
and covariate models in population pharmacokinetic analysis.
J Pharmacokin Biopharm 1994; 22: 165-177
Hope this helps.
Nancy
Nancy Sambol, Pharm.D.
Associate Clinical Professor
Director of Data Analysis Group