RE: Wrong model

From: Matt Hutmacher Date: July 12, 2002 technical Source: cognigencorp.com
From:"HUTMACHER, MATTHEW [Non-Pharmacia/1820]" Subject:RE: [NMusers] Wrong model Date:Fri, 12 Jul 2002 12:57:06 -0400 Hello Peter, Often CL is not badly biased, with volume being biased and estimated somewhere between Vc and Vss. Ka is often horribly estimated but its pathology does affect the estimation of CL (in my experience). See Kowalski and Hutmacher. Design evaluation for a population PK study using clinical trial simulations. Stats in Medicine 2001; 20:75-91 Hope this helps. Matt

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Jul 12, 2002 Peter Bonate Wrong model
Jul 12, 2002 Matt Hutmacher RE: Wrong model
Jul 12, 2002 Nancy Sambol Re: Wrong model
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