FYI - MEM for binary response with one obs/individual

From: Lewis B. Sheiner Date: September 15, 2001 technical Source: cognigencorp.com
From: Lewis B Sheiner <lewis@c255.ucsf.edu> Subject: FYI - MEM for binary response with one obs/individual Date: Sat, 15 Sep 2001 10:22:40 -0700 So, perhaps it can be done after all, but Stuart is not sanguine ...\
Quoted reply history
-------- Original Message -------- Date: Sat, 15 Sep 2001 04:21:02 -0700 (PDT) From: stuart@c255b.ucsf.edu To: dennis.fisher@durect.com, lewis@c255b.ucsf.edu >I'm basing my "can't be done" on the idea that the omega is unidentifable: >if you have 1 success, and 1 failure, how can you >know if the success will be a success the next time with p>.5 >(=> omega > 0) or with p=.5 (=> omega = 0)? > > Lewis The highly nonlinear nature of the logistic-type model often allows the inter- and intra-individual variability to be separated. In one example I just ran, I got legitimate estimates 90% of the time. However, as we have learned since the time of the Bailey-Gregg article in 1997, and as we report in our JPP article in last month's issue: When the amount of data per individual is very small, the estimates are not as good as those obtained when interindividual variability is omitted from the model. In the example I just ran, the estimates are indeed quite poor, so poor in fact as to suggest that it would be ill-advised to include interindividual-variability in the model. Stu
Sep 15, 2001 Lewis B. Sheiner FYI - MEM for binary response with one obs/individual
Sep 17, 2001 Lewis B. Sheiner 1 binary response/person
Sep 17, 2001 Nick Holford Re: 1 binary response/person
Sep 18, 2001 Lewis B. Sheiner Re: 1 binary response/person
Sep 18, 2001 Vladimir Piotrovskij RE: 1 binary response/person