Conversion of micro constants to macro constants

From: Atul Bhattaram Venkatesh Date: August 14, 2001 technical Source: cognigencorp.com
From: bvatul [mailto:bvatul@ufl.edu] Subject: Conversion of micro constants to macro constants Date: Tue, 14 Aug 2001 Hello All Could somebody share their views on this? I am analysing a data set (iv infusion) in NONMEM using a three compartment model for the drug and two compartment model for the metabolite using ADVAN6. How can I calculate the macro constants (alpha, beta, gamma) from the calculated microconstants (k10, k12, k21, k13, k31, k30)? I wish to estimate the half-life etc. Are there any reported papers on these type of results? Thanks in advance Atul

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Aug 14, 2001 Atul Bhattaram Venkatesh Conversion of micro constants to macro constants
Aug 14, 2001 William Bachman RE: Conversion of micro constants to macro constants
Aug 14, 2001 William Bachman RE: Conversion of micro constants to macro constants
Aug 14, 2001 William Bachman RE: Conversion of micro constants to macro constants
Aug 14, 2001 Joern Loetsch Re: Conversion of micro constants to macro constants
Aug 14, 2001 William Bachman RE: Conversion of micro constants to macro constants - YAC (yet a nother correction)
Aug 14, 2001 Janet Wade RE: Conversion of micro constants to macro constants
Aug 14, 2001 Lloyd Whitfield RE: Conversion of micro constants to macro constants
Aug 15, 2001 Lutz Harnisch AW: Conversion of micro constants to macro constants
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