Sample Size

From: Alison_Carter@eisai.com Subject: Sample Size Date: Mon, 12 Jun 2000 11:37:58 -0400 I am an experienced NONMEM user reagrding retrospective studies, however I am now planning a prospective study and I have a question regarding determining an appropriate sample size. I userstand the concept of performing simulations using different sampling strategies and sample sizes until the desired parameters are estimated to within an acceptable amount of error, but how do I determine what is an acceptable amount of error? Any help on this matter would be greatly appreciated. Thanks very much. Alison Carter