Take the Lead
Our Clinical Pharmacology Leads have key roles to play in influencing the
discovery and development of drugs. It is exciting, critical work and you could
be part of it.
Pfizer is a leader in Model Based Drug Development, and we are expanding its
influence in target validation and selection. We have a new position for a
talented individual at our Cambridge, UK, Research Unit.
In this key role you will serve as the Clinical Pharmacology Lead on
multidisciplinary development teams and provide clinical pharmacology expertise
and leadership to a project. You will work closely with clinicians and
statisticians to create clinical development plans that include assessments of
a drug's efficacy, safety, and commercial viability. In collaboration with
other quantitative clinical and nonclinical disciplines, the Clinical
Pharmacology Lead will integrate PK-PD knowledge from preclinical experiments,
clinical results, and meta-analyses of the literature to inform target
validation, human administration, and phase 2 study design and analysis.
In order to achieve these aims, candidates are responsible for the application
and development of innovative analytical methods to integrate knowledge of
pharmacokinetics, biopharmaceutics, pharmacodynamics, patient characteristics
and disease states to optimize doses, dosage regimens and study designs
throughout clinical drug development (including FIH single/multiple doses,
proof of concept, PK-PD, dose-ranging in patients, drug interactions, special
populations, food effects, etc.).
Clinical Pharmacology Leads routinely interact with internal leadership,
regulatory agencies, and external opinions leaders. We are expected to
influence the internal and external environment by advancing quantitative and
systems pharmacology and through presentations and publications.
The ideal candidates will be proficient communicators with a doctorate degree,
strong quantitative skills (e.g. experience in mechanistic modeling/systems
pharmacology, literature meta-analyses, population modeling, and clinical trial
simulations) and expertise in clinical pharmacology and/or pharmacometrics . We
encourage applicants from different disciplines including clinical
pharmacology, engineering, biostatistics, medicine, biology, etc. Candidates
with significant experience are sought as well as recent graduates. In addition
to professional challenge, we offer a culture that supports and encourages
ideas, and recognizes individual contribution.
The ideal candidates will be proficient communicators with a doctorate degree,
strong quantitative skills (e.g. experience in mechanistic modeling/systems
pharmacology, literature meta-analyses, population modeling, and clinical trial
simulations) and expertise in clinical pharmacology and/or pharmacometrics . We
encourage applicants from different disciplines including clinical
pharmacology, engineering, biostatistics, medicine, biology, etc. Candidates
with significant experience are sought as well as recent graduates. In addition
to professional challenge, we offer a culture that supports and encourages
ideas, and recognizes individual contribution.
All over the world, Pfizer colleagues are working together to positively impact
health for everyone, everywhere. Each position at Pfizer touches and
contributes to the success of our business and our world. That's why, as one of
the global leaders in the biopharmaceutical industry, Pfizer is committed to
seeking out inspired new talent who share our core values and mission of making
the world a healthier place.
To apply please visit the careers pages on
http://www.pfizercareers.com and enter the following job
opening number: 998065 or contact
[email protected]<mailto:[email protected]> Talent Acquisition
Specialist for more information, or the Clinical Pharmacology Hiring Manager
([email protected]<mailto:[email protected]>).