Pfizer Clinical Pharmacology Lead Position: Cambridge (UK)

Take the Lead Our Clinical Pharmacology Leads have key roles to play in influencing the discovery and development of drugs. It is exciting, critical work and you could be part of it. Pfizer is a leader in Model Based Drug Development, and we are expanding its influence in target validation and selection. We have a new position for a talented individual at our Cambridge, UK, Research Unit. In this key role you will serve as the Clinical Pharmacology Lead on multidisciplinary development teams and provide clinical pharmacology expertise and leadership to a project. You will work closely with clinicians and statisticians to create clinical development plans that include assessments of a drug's efficacy, safety, and commercial viability. In collaboration with other quantitative clinical and nonclinical disciplines, the Clinical Pharmacology Lead will integrate PK-PD knowledge from preclinical experiments, clinical results, and meta-analyses of the literature to inform target validation, human administration, and phase 2 study design and analysis. In order to achieve these aims, candidates are responsible for the application and development of innovative analytical methods to integrate knowledge of pharmacokinetics, biopharmaceutics, pharmacodynamics, patient characteristics and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development (including FIH single/multiple doses, proof of concept, PK-PD, dose-ranging in patients, drug interactions, special populations, food effects, etc.). Clinical Pharmacology Leads routinely interact with internal leadership, regulatory agencies, and external opinions leaders. We are expected to influence the internal and external environment by advancing quantitative and systems pharmacology and through presentations and publications. The ideal candidates will be proficient communicators with a doctorate degree, strong quantitative skills (e.g. experience in mechanistic modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations) and expertise in clinical pharmacology and/or pharmacometrics . We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc. Candidates with significant experience are sought as well as recent graduates. In addition to professional challenge, we offer a culture that supports and encourages ideas, and recognizes individual contribution. The ideal candidates will be proficient communicators with a doctorate degree, strong quantitative skills (e.g. experience in mechanistic modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations) and expertise in clinical pharmacology and/or pharmacometrics . We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc. Candidates with significant experience are sought as well as recent graduates. In addition to professional challenge, we offer a culture that supports and encourages ideas, and recognizes individual contribution. All over the world, Pfizer colleagues are working together to positively impact health for everyone, everywhere. Each position at Pfizer touches and contributes to the success of our business and our world. That's why, as one of the global leaders in the biopharmaceutical industry, Pfizer is committed to seeking out inspired new talent who share our core values and mission of making the world a healthier place. To apply please visit the careers pages on http://www.pfizercareers.com and enter the following job opening number: 998065 or contact [email protected]<mailto:[email protected]> Talent Acquisition Specialist for more information, or the Clinical Pharmacology Hiring Manager ([email protected]<mailto:[email protected]>).