The Centre of Excellence in Drug Safety and Pharmacokinetics (CentEx DSP) at
Servier has an opening position for a highly motivated Post-doc in Quantitative
Systems Pharmacology (QSP).
The candidate will be full-time dedicated to QSP modelling activities to
support pre-clinical and clinical development programmes. The candidate will
have strong relationships with other modellers (i.e. early phase, QSP and PBPK)
and stakeholders within Servier (i.e. clinicians, pharmacologists, oncologist,
immunologist).
Challenges
The candidate will be responsible for:
· Support and development of mechanistic QSP models within oncology and
immunology.
· Model evaluation, qualification and validation of ODE-based
mechanistic QSP models.
· Iterative implementation of relevant in-house data as well as
literature data for further model refinement.
· Model analysis, uncertainty assessment and documentation.
· Presenting QSP activities to internal/external experts in the field.
According to his/her experience, the candidate will also participate to:
· The improvement of modelling tools and methodological development
· Promotion of modelling activities within the Servier group
Skills and Experience
You hold a PhD in a relevant area (Systems Pharmacology/Biology, Biophysics or
Biomathematics, Biomedical or Biochemical Engineering, Computational Biology or
other fields related to dynamic mathematical modelling & simulation
approaches). Ideally, you have hands-on experience in quantitative biological
systems modelling within oncology, cell biology or immunology. You are fluent
in English, both orally and written, and have good communication and
presentation skills. The pharmacometrics group at Servier is located in France
(Suresnes near Paris and Orléans). Working knowledge of French is not a
requirement.
This post-doc position in Quantitative Systems Pharmacology requires good
knowledge of simulation and programming software such as Matlab and R.
Knowledge in Simbiology, SimCYP, GastroPlus or PKSim is an asset. Furthermore,
the position requires a good understanding of pharmacological, immunological,
cell biological or/and oncological principles.
You have an analytical mind-set and a strong desire to further develop and
apply modelling and simulation in drug development. You appreciate working in
teams of scientists with different backgrounds and the opportunity of expanding
your network at an international level.
We offer an exciting opportunity for developing your professional skills and
for working with projects with many challenges and with support from a range of
highly skilled professionals.
Contact
For further information, please contact Marylore Chenel:
[email protected]