Opening position for a 1.5-year post doc in QSP at Servier (France)

The Centre of Excellence in Drug Safety and Pharmacokinetics (CentEx DSP) at Servier has an opening position for a highly motivated Post-doc in Quantitative Systems Pharmacology (QSP). The candidate will be full-time dedicated to QSP modelling activities to support pre-clinical and clinical development programmes. The candidate will have strong relationships with other modellers (i.e. early phase, QSP and PBPK) and stakeholders within Servier (i.e. clinicians, pharmacologists, oncologist, immunologist). Challenges The candidate will be responsible for: · Support and development of mechanistic QSP models within oncology and immunology. · Model evaluation, qualification and validation of ODE-based mechanistic QSP models. · Iterative implementation of relevant in-house data as well as literature data for further model refinement. · Model analysis, uncertainty assessment and documentation. · Presenting QSP activities to internal/external experts in the field. According to his/her experience, the candidate will also participate to: · The improvement of modelling tools and methodological development · Promotion of modelling activities within the Servier group Skills and Experience You hold a PhD in a relevant area (Systems Pharmacology/Biology, Biophysics or Biomathematics, Biomedical or Biochemical Engineering, Computational Biology or other fields related to dynamic mathematical modelling & simulation approaches). Ideally, you have hands-on experience in quantitative biological systems modelling within oncology, cell biology or immunology. You are fluent in English, both orally and written, and have good communication and presentation skills. The pharmacometrics group at Servier is located in France (Suresnes near Paris and Orléans). Working knowledge of French is not a requirement. This post-doc position in Quantitative Systems Pharmacology requires good knowledge of simulation and programming software such as Matlab and R. Knowledge in Simbiology, SimCYP, GastroPlus or PKSim is an asset. Furthermore, the position requires a good understanding of pharmacological, immunological, cell biological or/and oncological principles. You have an analytical mind-set and a strong desire to further develop and apply modelling and simulation in drug development. You appreciate working in teams of scientists with different backgrounds and the opportunity of expanding your network at an international level. We offer an exciting opportunity for developing your professional skills and for working with projects with many challenges and with support from a range of highly skilled professionals. Contact For further information, please contact Marylore Chenel: [email protected]