Dear NM users,
Some time ago there was a test case of using NONMEM with Accellerant. Could
anyone please share reviews about using ACCELLERANT with NONMEM, in a
cluster environment of multi-core multi-CPUs?
Regards,
Santosh
NONMEM with ACCELLERANT
Santosh ACCELLERANT was developed by a company called ASPEED, which has been out of business for awhile now. ACCELERANT was actually a load balancing toolkit, which isn't especially relevant to NONMEM. But, they also were in the business of developing parallel software, and by all accounts were pretty good at it. They came out with two versions of ACCELLERANT for NONMEM (used ACCELERANT, but real trick was parallel NONMEM). Version 1 was not parallelized, just started with a variety of initial estimates and took the one that converged first (not very clever or useful IMHO). They had a least a beta of a true parallelized version ( http://www.ecpag.org/2006/5_MarkSale.pdf ). This worked, pretty well (again, in my humble opinion ;-)), and could have been run on pretty much any of the environments you mention, could also be run on a simple LAN, a grid computing environment or in theory, a VPN accross the internet. Mark Sale MD
Next Level Solutions, LLC
www.NextLevelSolns.com
919-846-9185
Quoted reply history
-------- Original Message --------
Subject: [NMusers] NONMEM with ACCELLERANT
From: Santosh < [email protected] >
Date: Tue, April 21, 2009 4:20 pm
To: [email protected]
Dear NM users, Some time ago there was a test case of using NONMEM with Accellerant. Could anyone please share reviews about using ACCELLERANT with NONMEM, in a cluster environment of multi-core multi-CPUs? Regards, Santosh
ACCELLERANT was able to run jobs across a cluster of Linux/UNIX systems.
If I remember correctly you needed a shared file systems, i.e. NFS, so
the data was available across all the systems and it used ssh (secure
shell) to run the job portions to the configured nodes in the "cluster".
Mark Sale - Next Level Solutions wrote:
>
> Guess I didn't actually answer your question. To my knowledge,
> ACCELERANT for NONMEM was never run on a cluster, only on a multi
> processor server. I'm only familiar with GSK's and ASPEED internal
> experience.
>
>
> Mark Sale MD
> Next Level Solutions, LLC
> www.NextLevelSolns.com http://www.NextLevelSolns.com
> 919-846-9185
>
Quoted reply history
> -------- Original Message --------
> Subject: [NMusers] NONMEM with ACCELLERANT
> From: Santosh <[email protected]>
> Date: Tue, April 21, 2009 4:20 pm
> To: [email protected]
>
> Dear NM users,
> Some time ago there was a test case of using NONMEM with
> Accellerant. Could anyone please share reviews about using
> ACCELLERANT with NONMEM, in a cluster environment of multi-core
> multi-CPUs?
>
> Regards,
> Santosh
>
--
Darin Perusich
Unix Systems Administrator
Cognigen Corporation
395 Youngs Rd.
Williamsville, NY 14221
Phone: 716-633-3463
Email: [email protected]
Thanks so much for your responses. Have there been other efforts or are
there other efforts in the pipeline to port NONMEM to multi-core multi-CPU
"Linux/Unix" environment? If yes, could you please provide the names of the
vendors?
Regards,
Santosh
Quoted reply history
On Wed, Apr 22, 2009 at 6:33 AM, Darin Perusich <
[email protected]> wrote:
> ACCELLERANT was able to run jobs across a cluster of Linux/UNIX systems.
> If I remember correctly you needed a shared file systems, i.e. NFS, so
> the data was available across all the systems and it used ssh (secure
> shell) to run the job portions to the configured nodes in the "cluster".
>
> Mark Sale - Next Level Solutions wrote:
> >
> > Guess I didn't actually answer your question. To my knowledge,
> > ACCELERANT for NONMEM was never run on a cluster, only on a multi
> > processor server. I'm only familiar with GSK's and ASPEED internal
> > experience.
> >
> >
> > Mark Sale MD
> > Next Level Solutions, LLC
> > www.NextLevelSolns.com http://www.NextLevelSolns.com
> > 919-846-9185
> >
> > -------- Original Message --------
> > Subject: [NMusers] NONMEM with ACCELLERANT
> > From: Santosh <[email protected]>
> > Date: Tue, April 21, 2009 4:20 pm
> > To: [email protected]
> >
> > Dear NM users,
> > Some time ago there was a test case of using NONMEM with
> > Accellerant. Could anyone please share reviews about using
> > ACCELLERANT with NONMEM, in a cluster environment of multi-core
> > multi-CPUs?
> >
> > Regards,
> > Santosh
> >
>
> --
> Darin Perusich
> Unix Systems Administrator
> Cognigen Corporation
> 395 Youngs Rd.
> Williamsville, NY 14221
> Phone: 716-633-3463
> Email: [email protected]
>