RE: NONMEM with ACCELLERANT

Santosh ACCELLERANT was developed by a company called ASPEED, which has been out of business for awhile now. ACCELERANT was actually a load balancing toolkit, which isn't especially relevant to NONMEM. But, they also were in the business of developing parallel software, and by all accounts were pretty good at it. They came out with two versions of ACCELLERANT for NONMEM (used ACCELERANT, but real trick was parallel NONMEM). Version 1 was not parallelized, just started with a variety of initial estimates and took the one that converged first (not very clever or useful IMHO). They had a least a beta of a true parallelized version ( http://www.ecpag.org/2006/5_MarkSale.pdf ). This worked, pretty well (again, in my humble opinion ;-)), and could have been run on pretty much any of the environments you mention, could also be run on a simple LAN, a grid computing environment or in theory, a VPN accross the internet. Mark Sale MD Next Level Solutions, LLC www.NextLevelSolns.com 919-846-9185