NM7 ISODA error code -1 and -6

3 messages 2 people Latest: Nov 02, 2009

NM7 ISODA error code -1 and -6

From: Sam Liao Date: November 01, 2009 technical
Dear NONMEM team: I am using NONMEM 7.10, ADVAN13 on a PK model with very stiff functions. I am getting this error in ISODA code -1 and sometime -6 in some of the subjects. Can someone please tell me what this mean and how to fix it. Best regards, Sam Liao Pharmax Research

NM7 ISODA error code -1 and -6

From: Sam Liao Date: November 02, 2009 technical
Dear NONMEM team: I am using NONMEM 7.10, ADVAN13 on a PK model with very stiff functions. I am getting this error in ISODA code -1 and sometime -6 in some of the subjects. Can someone please tell me what this mean and how to fix it. Best regards, Sam Liao Pharmax Research

RE: NM7 ISODA error code -1 and -6

From: Robert Bauer Date: November 02, 2009 technical
If you get this error only occasionally, and the problem still runs, it may not be in issue. Alternatively, you can try different TOL settings. Finally, if these do not work, you should fall back on advan9. Robert J. Bauer, Ph.D. Vice President, Pharmacometrics ICON Development Solutions Tel: (215) 616-6428 Mob: (925) 286-0769 Email: [email protected] Web: www.icondevsolutions.com
Quoted reply history
________________________________ From: [email protected] [mailto:[email protected]] On Behalf Of Sam Liao Sent: Sunday, November 01, 2009 11:00 PM To: 'nmusers' Subject: [NMusers] NM7 ISODA error code -1 and -6 Dear NONMEM team: I am using NONMEM 7.10, ADVAN13 on a PK model with very stiff functions. I am getting this error in ISODA code -1 and sometime -6 in some of the subjects. Can someone please tell me what this mean and how to fix it. Best regards, Sam Liao Pharmax Research