Dear NONMEM Users:
1) NONMEM 7.3 has been available since December 2013, and many of you have
been using the latest features that it has to offer. Minor bugs have been
reported, for which there are work-arounds. These are published at the
following location:
ftp://nonmem.iconplc.com/Public/nonmem730/nm730_bug_list.pdf
Bugs pertaining to $LEVEL, $THETAR, $SIM BOOTSRAP, and $ETAS/PHIS are
described, and work-arounds are provided.
2) Please find updated utility programs at
ftp://nonmem.iconplc.com/Public/utilities
and read
readme_utilities.pdf<ftp://nonmem.iconplc.com/Public/utilities/readme_utilities.pdf>
An improved version of finedata allowing one to incorporate extra doses to a
data file, and a utility called doexpand allowing one to easily incorporate
repetitive indexed code using meta commands are particularly useful for
modeling delayed differential equations.
3) Some typographical errors, and some extra information on the use of the
t-distribution for importance sampling ($EST DF option) have been incorporated
in an updated version of nm730.pdf,
located at
ftp://nonmem.iconplc.com/Public/nonmem730/Latest_User_Documents/guides/
Also, guide I.pdf was improperly constructed, and has been now corrected.
Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics, R&D
ICON Development Solutions
7740 Milestone Parkway
Suite 150
Hanover, MD 21076
Tel: (215) 616-6428
Mob: (925) 286-0769
Email: [email protected]<mailto:[email protected]>
Web: http://www.iconplc.com/