Dear nmusers,
I am using NONMEM 7.3 for a simple PD modeling analysis. I was able to run this
file in NONMEM 7.2 but after the switching, I got this error message. NONMEM
asked for the *tabdn101 file (my mod file name is dn101.mod). Can you please
help? Thank you very much!
0ITERATION NO.: 15 OBJECTIVE VALUE: -2830.13313592389 NO. OF FUNC.
EVALS.: 6
CUMULATIVE NO. OF FUNC. EVALS.: 114
NPARAMETR: 9.6232E-04 9.4126E-03 1.9896E+00 1.3094E+00 6.2668E-02
PARAMETER: -1.7824E+00 2.4309E+00 4.4397E-01 -3.9158E-01 -1.3366E-01
GRADIENT: 8.6164E-02 -4.8788E-02 8.0264E-02 -8.6181E-02 5.0536E-02
Elapsed estimation time in seconds: 2.61
Elapsed covariance time in seconds: 1.75
1 file(s) copied.
1 file(s) copied.
1 file(s) copied.
*tabdn101
The system cannot find the file specified.
0 file(s) copied.
Pirana: All runs finished / submitted.
Done
I include here my mod file as well. Thank you
$PROB RUN# finalnm
$INPUT C ID TIME PSA PSAbase DV
$DATA dn101final2.csv IGNORE=C
$PRED
KL = THETA(1)*EXP(ETA(1))
KD = THETA(2)*EXP(ETA(2))
IPRED = EXP( KL * TIME ) + EXP( - KD * TIME ) - 1
Y = IPRED + ERR(1)
DEL=0
IF (F.EQ.0) DEL=1
W=Y
IRES=DV-IPRED
IWRES=IRES/(W+DEL)
$THETA
(0,0.006,0.1) ; KL
(0,0.001,0.1) ; KD
$OMEGA
1 ;[P]
3.5 ;[P]
$SIGMA
0.1
$EST PRINT=10 MAXEVAL=9999 METHOD=1 INTER
$COV
$TABLE ID TIME IPRED WRES CWRES KL KD ETA1 ETA2 ONEHEADER NOPRINT FILE=
fulldata.tab
$TABLE ID ETA1 ETA2 CWRES ONEHEADER NOPRINT FILE=PATAB_1
$TABLE ID CWRES ONEHEADER NOPRINT FILE=COTAB_1
$TABLE ID TIME IPRED IWRES CWRES ONEHEADER NOPRINT FILE=SDTAB_1
$TABLE ID ONEHEADER NOPRINT FILE=CATAB_1
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