Error message since switching to NONMEM 7.3
Dear nmusers,
I am using NONMEM 7.3 for a simple PD modeling analysis. I was able to run this
file in NONMEM 7.2 but after the switching, I got this error message. NONMEM
asked for the *tabdn101 file (my mod file name is dn101.mod). Can you please
help? Thank you very much!
0ITERATION NO.: 15 OBJECTIVE VALUE: -2830.13313592389 NO. OF FUNC.
EVALS.: 6
CUMULATIVE NO. OF FUNC. EVALS.: 114
NPARAMETR: 9.6232E-04 9.4126E-03 1.9896E+00 1.3094E+00 6.2668E-02
PARAMETER: -1.7824E+00 2.4309E+00 4.4397E-01 -3.9158E-01 -1.3366E-01
GRADIENT: 8.6164E-02 -4.8788E-02 8.0264E-02 -8.6181E-02 5.0536E-02
Elapsed estimation time in seconds: 2.61
Elapsed covariance time in seconds: 1.75
1 file(s) copied.
1 file(s) copied.
1 file(s) copied.
*tabdn101
The system cannot find the file specified.
0 file(s) copied.
Pirana: All runs finished / submitted.
Done
I include here my mod file as well. Thank you
$PROB RUN# finalnm
$INPUT C ID TIME PSA PSAbase DV
$DATA dn101final2.csv IGNORE=C
$PRED
KL = THETA(1)*EXP(ETA(1))
KD = THETA(2)*EXP(ETA(2))
IPRED = EXP( KL * TIME ) + EXP( - KD * TIME ) - 1
Y = IPRED + ERR(1)
DEL=0
IF (F.EQ.0) DEL=1
W=Y
IRES=DV-IPRED
IWRES=IRES/(W+DEL)
$THETA
(0,0.006,0.1) ; KL
(0,0.001,0.1) ; KD
$OMEGA
1 ;[P]
3.5 ;[P]
$SIGMA
0.1
$EST PRINT=10 MAXEVAL=9999 METHOD=1 INTER
$COV
$TABLE ID TIME IPRED WRES CWRES KL KD ETA1 ETA2 ONEHEADER NOPRINT FILE=
fulldata.tab
$TABLE ID ETA1 ETA2 CWRES ONEHEADER NOPRINT FILE=PATAB_1
$TABLE ID CWRES ONEHEADER NOPRINT FILE=COTAB_1
$TABLE ID TIME IPRED IWRES CWRES ONEHEADER NOPRINT FILE=SDTAB_1
$TABLE ID ONEHEADER NOPRINT FILE=CATAB_1
********************************************************************************
This e-mail is intended only for the use of the individual or entity to which
it is addressed and may contain information that is privileged and confidential.
If the reader of this e-mail message is not the intended recipient, you are
hereby notified that any dissemination, distribution or copying of this
communication is prohibited. If you have received this e-mail in error, please
notify the sender and destroy all copies of the transmittal.
Thank you
University of Chicago Medicine and Biological Sciences
********************************************************************************