From: "Dr. Olaf Kuhlmann" <olaf.kuhlmann@medizin.uni-halle.de>
Subject: Characters in error are: FWORK
Date: Mon, 18 Jun 2001 12:02:48 +0000
Dear nmusers,
I am a beginner in using NONMEM and have some problems modeling my PK PD data (ADVAN 3). I have 59 subjects, for each subject 2-3 plasma data at different time points, in total 153 records( and 10 data items).
During the run the following message arises:
"an error was found in the control statements. The characters in error are: FWORK.
36 ERROR has occurred while creating required files" (two computers tried, same result)
--> the error did not arise when I omit the first/or last 20 subjects. Is there a limitation in no. of data records? (chapter 6, page 50 of the introductory says NO).
--> second question (for my better understanding). When I omit the first (or last) 20 subjects, and everything is fine until the output file, I find in this file in the line:
No. of Data Recs in data set: --> the number 98
but some lines later:
Tot. No. of OBS Recs: --> just the number 63 (which is the correct number in my data file)
What is the reason for this difference?
Please help me...
Thanks a lot in advance
OLAF
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Dr.rer.nat. Olaf Kuhlmann (Dipl.-Biol.)
Martin-Luther-Universitaet Halle-Wittenberg
Medizinische Fakultaet
Institut fuer Pharmakologie und Toxikologie
Sektion Pharmakokinetik
Magdeburger Str. 4
06097 Halle/Germany
Tel.: 0345-5574091
FAX : 0345-5571835
E-mail: olaf.kuhlmann@medizin.uni-halle.de
Webpage: http://www.medizin.uni-halle.de/pharmakin/Kuhlmann.htm
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