I am attempting to generate 100 iterations of a concentration curve for
multiple doses in a single individual.
In order to reflect the input of the extended release dosage form from
the dissolution data, I have multiple infusions into the gut
representing the amount released in each of these units of time based
on the dissolution data. For 14 doses, then, I am reproducing this,
and the data file is quite long (687 records). I have therefore had to
increase NSIZES with respect to the number of observations, as well as
increasing buffers 1,2, and 6.
I will need to import the results into R, since excel can't take
687X100 lines of output. However, regardless of whether I look at my
.txt output, or importing it as far as I can into Excel, the output
includes asterisks
ID TIME CMPT IPRE DV PRED RES WRES
1.0000E+00 0.0000E+00 1.0000E+00 0.0000E+00 0.0000E+00
0.0000E+00 0.0000E+00 0.0000E+00
1.0000E+00 2.5000E-01 2.0000E+00 1.1193E-05 -5.6330E-02
3.0897E-05 -5.6361E-02 0.0000E+00
1.0000E+00 2.5000E-01 3.0000E+00 3.6747E-09 3.6747E-09
1.0143E-08 -6.4683E-09 0.0000E+00
1.0000E+00 2.5000E-01 1.0000E+00 1.1193E-05 0.0000E+00
3.0897E-05 0.0000E+00 0.0000E+00
1.0000E+00 5.0000E-01 2.0000E+00 *********** ***********
*********** *********** 0.0000E+00
1.0000E+00 5.0000E-01 3.0000E+00 *********** ***********
*********** *********** 0.0000E+00
Can anyone explain why I am getting the asterisks in the output (even
with only one simulation? Everything was fine before I messed with
the buffers (relevant part of SIZES below):
C NO: MAX NO. OF OBSERVATION RECORDS / INDIVIDUAL RECORD
C IF NO IS CHANGED, ALSO RECOMPILE NM-TRAN, NM-TRAN LIBRARY
PARAMETER (NOu0)
...
C LIM1: SIZE OF BUFFER 1
PARAMETER (LIM10)
C LIM2: SIZE OF BUFFER 2
PARAMETER (LIM20)
C LIM3: SIZE OF BUFFER 3
PARAMETER (LIM3 0)
C LIM4: SIZE OF BUFFER 4
PARAMETER (LIM4P)
C LIM5: SIZE OF BUFFER 5
PARAMETER (LIM5 0)
C LIM6: SIZE OF BUFFER 6
PARAMETER (LIM60)
C LIM7: SIZE OF BUFFER 7
PARAMETER (LIM7=2)
C LIM8: SIZE OF BUFFER 8
PARAMETER (LIM8 0)
C LIM11: SIZE OF BUFFER 11
PARAMETER (LIM11%)
C LIM13: SIZE OF BUFFER 13
PARAMETER (LIM13=1)
C LIM15: SIZE OF BUFFER 15
PARAMETER (LIM15=1)
C LIM16: SIZE OF BUFFER 16
PARAMETER (LIM16@0)
Thanks very much
Paul
--
Paul R
Paul R.
Hutson, Pharm.D.
Associate
Professor
UW School
of Pharmacy
777
Highland Avenue
Madison
WI 53705-2222
Tel 608.263.2496
Fax
608.265.5421
Pager
608.265.7000, p7856