Group:
I am trying to run a POPPK analysis on sublingual data for pediatric patients.
NONMEM is very new for me. I am debating whether it is appropriate to use ADVAN
1 or ADVAN2 for subligual administration. Neither fit the concept perfectly.
Should the CTL streams be modified in any way?
Thanks in advance.
Varsha Mehta, MS(CRDSA), Pharm.D., FCCP
Clinical Associate Professor
Pharmacy, Pediatrics and Communicable Diseases
Clinical Pharmacist Neonatal Critical Care
University of Michigan
(O) 734-936-8985
(F) 734-936-6946
[email protected]
**********************************************************
Electronic Mail is not secure, may not be read every day, and should not be
used for urgent or sensitive issues
ADVAN 1 or ADVAN 2 for sublingual data
Just consider the sublingual admin to be an extravascular dose. ADVAN2
has a depot for extravascular dosing.
Quoted reply history
-----Original Message-----
From: [email protected] [mailto:[email protected]]
On Behalf Of Varsha Mehta
Sent: Thursday, January 15, 2009 12:41 PM
To: [email protected]
Subject: [NMusers] ADVAN 1 or ADVAN 2 for sublingual data
Group:
I am trying to run a POPPK analysis on sublingual data for pediatric
patients. NONMEM is very new for me. I am debating whether it is
appropriate to use ADVAN 1 or ADVAN2 for subligual administration.
Neither fit the concept perfectly.
Should the CTL streams be modified in any way?
Thanks in advance.
Varsha Mehta, MS(CRDSA), Pharm.D., FCCP
Clinical Associate Professor
Pharmacy, Pediatrics and Communicable Diseases
Clinical Pharmacist Neonatal Critical Care
University of Michigan
(O) 734-936-8985
(F) 734-936-6946
[email protected]
**********************************************************
Electronic Mail is not secure, may not be read every day, and should not
be used for urgent or sensitive issues