computation of exponential error model for RUV

From: Guidi Monia Date: July 19, 2021 technical Source: mail-archive.com
Dear colleagues, We would like to compare the NONMEM predictions with those obtained by a Bayesian TDM software for models describing the residual unexplained variability with exponential errors. We need to know if NONMEM performs a first order Taylor expansion of the exponential error when data are fitted by the FOCE method: Y=F*EXP(EPS(1)) -> Y= F*(1+EPS(1)). Could someone help with this? Thanks in advance Monia Monia Guidi, PhD Pharmacometrician Service of Clinical Pharmacology | University Hospital and University of Lausanne Center of research and innovation in Clinical Pharmaceutical Sciences | University Hospital and University of Lausanne BU17 01/193 CH-1011 Lausanne email: [email protected]<mailto:[email protected]> tel: +41 21 314 38 97 CHUV centre hospitalier universitaire vaudois [/var/folders/mv/mxzxwndj1w761kc51dsd0hdm0000gp/T/com.microsoft.Outlook/WebArchiveCopyPasteTempFiles/[email protected]]
Jul 19, 2021 Guidi Monia computation of exponential error model for RUV
Jul 19, 2021 Jakob Ribbing Re: computation of exponential error model for RUV
Jul 19, 2021 Leonid Gibiansky Re: computation of exponential error model for RUV
Jul 19, 2021 Luann Phillips RE: computation of exponential error model for RUV