computation of exponential error model for RUV
Dear colleagues,
We would like to compare the NONMEM predictions with those obtained by a
Bayesian TDM software for models describing the residual unexplained
variability with exponential errors.
We need to know if NONMEM performs a first order Taylor expansion of the
exponential error when data are fitted by the FOCE method:
Y=F*EXP(EPS(1)) -> Y= F*(1+EPS(1)).
Could someone help with this?
Thanks in advance
Monia
Monia Guidi, PhD
Pharmacometrician
Service of Clinical Pharmacology | University Hospital and University of
Lausanne
Center of research and innovation in Clinical Pharmaceutical Sciences |
University Hospital and University of Lausanne
BU17 01/193
CH-1011 Lausanne
email: [email protected]<mailto:[email protected]>
tel: +41 21 314 38 97
CHUV
centre hospitalier universitaire vaudois
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