Re: Troubleshooting installation of nonmembers 7.5 on Mac with silicon M1 CPU

> On Apr 28, 2021, at 11:20 AM, Mu'taz Jaber <[email protected]> wrote: > > Hi Rob: > > The following worked for me ( Anything inside ``` refers to a command line) > > You have at the beginning to locate the file in the system > > ``` > locate libquadmath.0.dylib > ``` > > Then you can check where it is found, usually its in the > "usr/local/Cellar/gcc/10.2.0_4/lib/gcc/10/libquadmath.0.dylib" > > Thus, you link it where nonmem wants it to be > ``` > ln usr/local/Cellar/gcc/10.2.0_4/lib/gcc/10/libquadmath.0.dylib > /usr/local/gfortran/lib/libquadmath.0.dylib > ``` > Here, you go back to the original setup > > cd ../nm75CD > > Then > > ``` > sh SETUP75std $HOME/Downloads/nm75CD $HOME/nm75 gfortran > ``` > > Hope it works for you! > Mutaz > ----------------------------------- > Mutaz M. Jaber, PharmD. > PhD student, Pharmacometrics > Experimental and Clinical Pharmacology > University of Minnesota > 717 Delaware St SE; Room 468 > Minneapolis, MN 55414 > Email: [email protected] > > > ~ Stay curious > > > On Wed, Apr 28, 2021 at 6:14 AM Heine, Rob ter <[email protected]> > wrote: > Hi Chandramouli, > > > > Xcode and command line tools were already installed (before nonmem > installation) using the “xcode-select --install” command. Again running this > command results in “xcode-select: error: command line tools are already > installed” and does not place the libraries in the folder nonmem installation > script is referring to. > > > > Sincerely, > > Rob > > Van: Chandramouli Radhakrishnan <[email protected]> > Datum: woensdag 28 april 2021 om 12:57 > Aan: Teijo Saari <[email protected]>, "Heine, Rob ter" > <[email protected]>, "[email protected]" <[email protected]> > Onderwerp: RE: [NMusers] Troubleshooting installation of nonmembers 7.5 on > Mac with silicon M1 CPU > > > > Please try this option - > > > > Dynamic libraries changed on Big Sur so the linker could not find libSystem. > You have to install the right SDKs by running `xcode-select --install` (see > also: https://developer.ap...s/thread/655588en > https://github.com/p...c/issues/3684). > > > > Chandramouli > > > > From: [email protected] <[email protected]> On Behalf > Of Teijo Saari > Sent: Wednesday, April 28, 2021 8:28 PM > To: Heine, Rob ter <[email protected]>; [email protected] > Subject: Re: [NMusers] Troubleshooting installation of nonmembers 7.5 on Mac > with silicon M1 CPU > > > > CAUTION: This email originated from outside of Certara. Do not click links or > open attachments unless you recognize the sender and know the content is safe. > > > > > > Might work. I did fresh installation after hearing so much about problems > with recent OSX and Xcode. > > Teijo > > On 28.4.2021 12.54, Heine, Rob ter wrote: > > Hi Teijo, > > > > I did install gfortran again, but it did not help. Should I remove xcode as > well? > > > > Sincerely, > > Rob > > > > Van: Teijo Saari <[email protected]> > Datum: woensdag 28 april 2021 om 11:19 > Aan: "Heine, Rob ter" <[email protected]>, "[email protected]" > <[email protected]> > Onderwerp: Re: [NMusers] Troubleshooting installation of nonmembers 7.5 on > Mac with silicon M1 CPU > > > > Dear Rob. > > I got this error solved previously by installing also gfortran anew. My > impression was that the xcode installation messed gfortran somehow up. > > Best wishes, > > Teijo > > On 28.4.2021 11.55, Heine, Rob ter wrote: > > Hi all, > > > > I am trying to install nonmem 7.5 on my new mac, with an Apple silicon (M1) > CPU, but I am unsuccessful thusfar. > > > > I have done the following: > > > > • Installed xcode command line tools > • Installed gfortran for silicon m1 CPUs from > https://github.com/fxcoudert/gfortran-for-macOS/releases/tag/11-arm-alpha2 > • Followed the instructions for the right path, and copied the files > from https://nonmem.iconplc.com/nonmem750/MACOSX/ to the right folder inside > the nonmem installation folder nm750cd, as instructed by the > readme_MACOSX.txt file > • Started the installation from a terminal window using the command > “sudo /bin/bash SETUP75std $HOME/Downloads/nm750CD $HOME/nm750 gfortran y ar > same rec i” > > > However, installation fails with the following message: > > Step 6. Compile resource files > > SETUP75std: line 523: 15300 Abort trap: 6 ./install 2 $zf $zu $f > "$op" "$mod" Linux "$u -a" o $pipe x > $msgs 2>&1 > > Compile of resource files failed. > > > > Please look for error messages in /Users/robterheine/nm750/compilemsgs.txt > and /Users/robterheine/nm750/finishmsgs.txt > > > > If I open these message files I see the following: > > dyld: Library not loaded: /usr/local/gfortran/lib/libquadmath.0.dylib > > Referenced from: /Users/robterheine/nm750/./install > > Reason: image not found > > > > It indeed seems that libqyadmath.0.dylib is not present on my drive. > > > > Does anyone have suggestions how to get the installation working? > > > > Sincerely, > > Rob > > De informatie in dit bericht is uitsluitend bestemd voor de geadresseerde. > Aan dit bericht en de bijlagen kunnen geen rechten worden ontleend. Heeft u > deze e-mail onbedoeld ontvangen? Dan verzoeken wij u het te vernietigen en de > afzender te informeren. 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Dan verzoeken wij u het te vernietigen en de > afzender te informeren. Openbaar maken, kopiëren en verspreiden van deze > e-mail of informatie uit deze e-mail is alleen toegestaan met voorafgaande > schriftelijke toestemming van de afzender. Het Radboudumc staat geregistreerd > bij de Kamer van Koophandel in het handelsregister onder nummer 80262783. > > The content of this message is intended solely for the addressee. No rights > can be derived from this message or its attachments. If you are not the > intended recipient, we kindly request you to delete the message and inform > the sender. It is strictly prohibited to disclose, copy or distribute this > email or the information inside it, without a written consent from the > sender. Radboud university medical center is registered with the Dutch > Chamber of Commerce trade register with number 80262783. > > De informatie in dit bericht is uitsluitend bestemd voor de geadresseerde. > Aan dit bericht en de bijlagen kunnen geen rechten worden ontleend. Heeft u > deze e-mail onbedoeld ontvangen? Dan verzoeken wij u het te vernietigen en de > afzender te informeren. Openbaar maken, kopiëren en verspreiden van deze > e-mail of informatie uit deze e-mail is alleen toegestaan met voorafgaande > schriftelijke toestemming van de afzender. Het Radboudumc staat geregistreerd > bij de Kamer van Koophandel in het handelsregister onder nummer 80262783. > > The content of this message is intended solely for the addressee. No rights > can be derived from this message or its attachments. If you are not the > intended recipient, we kindly request you to delete the message and inform > the sender. It is strictly prohibited to disclose, copy or distribute this > email or the information inside it, without a written consent from the > sender. Radboud university medical center is registered with the Dutch > Chamber of Commerce trade register with number 80262783. >