Re: Troubleshooting installation of nonmembers 7.5 on Mac with silicon M1 CPU
Hi Rob:
The following worked for me ( Anything inside ``` refers to a command line)
You have at the beginning to locate the file in the system
```
locate libquadmath.0.dylib
```
Then you can check where it is found, usually its in the
"usr/local/Cellar/gcc/10.2.0_4/lib/gcc/10/libquadmath.0.dylib"
Thus, you link it where nonmem wants it to be
```
ln usr/local/Cellar/gcc/10.2.0_4/lib/gcc/10/libquadmath.0.dylib
/usr/local/gfortran/lib/libquadmath.0.dylib
```
Here, you go back to the original setup
cd ../nm75CD
Then
```
sh SETUP75std $HOME/Downloads/nm75CD $HOME/nm75 gfortran
```
Hope it works for you!
Mutaz
*-----------------------------------*
*Mutaz M. Jaber, PharmD.*
*PhD student, Pharmacometrics*
*Experimental and Clinical Pharmacology*
*University of Minnesota *
*717 Delaware St SE; Room 468*
*Minneapolis, MN 55414*
*Email: [email protected] <[email protected]>*
*~ Stay curious*
Quoted reply history
On Wed, Apr 28, 2021 at 6:14 AM Heine, Rob ter <[email protected]>
wrote:
> Hi Chandramouli,
>
>
>
> Xcode and command line tools were already installed (before nonmem
> installation) using the “xcode-select --install” command. Again running
> this command results in “xcode-select: error: command line tools are
> already installed” and does not place the libraries in the folder nonmem
> installation script is referring to.
>
>
>
> Sincerely,
>
> Rob
>
> *Van: *Chandramouli Radhakrishnan <[email protected]>
> *Datum: *woensdag 28 april 2021 om 12:57
> *Aan: *Teijo Saari <[email protected]>, "Heine, Rob ter" <
> [email protected]>, "[email protected]" <
> [email protected]>
> *Onderwerp: *RE: [NMusers] Troubleshooting installation of nonmembers 7.5
> on Mac with silicon M1 CPU
>
>
>
> Please try this option -
>
>
>
> Dynamic libraries changed on Big Sur so the linker could not find
> libSystem. You have to install the right SDKs by running `xcode-select
> --install` (see also: https://developer.ap...s/thread/655588
> https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdeveloper.apple.com%2Fforums%2Fthread%2F655588&data=04%7C01%7CR.terHeine%40radboudumc.nl%7C97f050740d5e48891c5308d90a3472ae%7Cb208fe69471e48c48d87025e9b9a157f%7C1%7C0%7C637552042657380932%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=cLP2qOCd%2BgB%2FHe58EJ7jkBzCq%2F6d%2FSFh2qL4nbaHpnQ%3D&reserved=0
> en https://github.com/p...c/issues/3684).
> https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgithub.com%2Fponylang%2Fponyc%2Fissues%2F3684).&data=04%7C01%7CR.terHeine%40radboudumc.nl%7C97f050740d5e48891c5308d90a3472ae%7Cb208fe69471e48c48d87025e9b9a157f%7C1%7C0%7C637552042657390886%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=FCDfrT84%2BtjFy3KAeDu2WtLq9qYYxOAYxc1jRsQF%2Bow%3D&reserved=0
>
>
>
> Chandramouli
>
>
>
> *From:* [email protected] <[email protected]> *On
> Behalf Of *Teijo Saari
> *Sent:* Wednesday, April 28, 2021 8:28 PM
> *To:* Heine, Rob ter <[email protected]>; [email protected]
> *Subject:* Re: [NMusers] Troubleshooting installation of nonmembers 7.5
> on Mac with silicon M1 CPU
>
>
>
> CAUTION: This email originated from outside of Certara. Do not click
> links or open attachments unless you recognize the sender and know the
> content is safe.
>
>
>
>
>
> Might work. I did fresh installation after hearing so much about problems
> with recent OSX and Xcode.
>
> Teijo
>
> On 28.4.2021 12.54, Heine, Rob ter wrote:
>
> Hi Teijo,
>
>
>
> I did install gfortran again, but it did not help. Should I remove xcode
> as well?
>
>
>
> Sincerely,
>
> Rob
>
>
>
> *Van: *Teijo Saari <[email protected]> <[email protected]>
> *Datum: *woensdag 28 april 2021 om 11:19
> *Aan: *"Heine, Rob ter" <[email protected]>
> <[email protected]>, "[email protected]"
> <[email protected]> <[email protected]> <[email protected]>
> *Onderwerp: *Re: [NMusers] Troubleshooting installation of nonmembers 7.5
> on Mac with silicon M1 CPU
>
>
>
> Dear Rob.
>
> I got this error solved previously by installing also gfortran anew. My
> impression was that the xcode installation messed gfortran somehow up.
>
> Best wishes,
>
> Teijo
>
> On 28.4.2021 11.55, Heine, Rob ter wrote:
>
> Hi all,
>
>
>
> I am trying to install nonmem 7.5 on my new mac, with an Apple silicon
> (M1) CPU, but I am unsuccessful thusfar.
>
>
>
> I have done the following:
>
>
>
> 1. Installed xcode command line tools
> 2. Installed gfortran for silicon m1 CPUs from
> https://github.com/fxcoudert/gfortran-for-macOS/releases/tag/11-arm-alpha2
>
> https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgithub.com%2Ffxcoudert%2Fgfortran-for-macOS%2Freleases%2Ftag%2F11-arm-alpha2&data=04%7C01%7CR.terHeine%40radboudumc.nl%7C97f050740d5e48891c5308d90a3472ae%7Cb208fe69471e48c48d87025e9b9a157f%7C1%7C0%7C637552042657390886%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=cRWlNNXbCnQ0jhka3iI4UmIWf8K6hznGULguUN8r37Y%3D&reserved=0
> 3. Followed the instructions for the right path, and copied the files
> from https://nonmem.iconplc.com/nonmem750/MACOSX/
>
> https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fnonmem.iconplc.com%2Fnonmem750%2FMACOSX%2F&data=04%7C01%7CR.terHeine%40radboudumc.nl%7C97f050740d5e48891c5308d90a3472ae%7Cb208fe69471e48c48d87025e9b9a157f%7C1%7C0%7C637552042657390886%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=0ODaN88jjk4%2FOdh6vKF9ZswipI5z0D%2FMjBQ5wfMq8bk%3D&reserved=0
> to the right folder inside the nonmem installation folder nm750cd, as
> instructed by the readme_MACOSX.txt file
> 4. Started the installation from a terminal window using the command
> “sudo /bin/bash SETUP75std $HOME/Downloads/nm750CD $HOME/nm750 gfortran y
> ar same rec i”
>
>
>
> However, installation fails with the following message:
>
> Step 6. Compile resource files
>
> SETUP75std: line 523: 15300 Abort trap: 6 ./install 2 $zf $zu
> $f "$op" "$mod" Linux "$u -a" o $pipe x > $msgs 2>&1
>
> Compile of resource files failed.
>
>
>
> Please look for error messages in /Users/robterheine/nm750/compilemsgs.txt
> and /Users/robterheine/nm750/finishmsgs.txt
>
>
>
> If I open these message files I see the following:
>
> dyld: Library not loaded: /usr/local/gfortran/lib/libquadmath.0.dylib
>
> Referenced from: /Users/robterheine/nm750/./install
>
> Reason: image not found
>
>
>
> It indeed seems that libqyadmath.0.dylib is not present on my drive.
>
>
>
> Does anyone have suggestions how to get the installation working?
>
>
>
> Sincerely,
>
> Rob
>
>
>
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