SEED status with SAEM method
Hello nmusers,
I've tried to test the SAEM method on my dataset (1 sample for each ID)
with different SEED status. Sometimes, I've got good results (with RSE
<50%), but sometimes I can't get it.
Example:
$EST METHOD=SAEM INTERACTION NBURN=3000 NITER=500 AUTO=1 PRINT=100
SEED=123456789
$EST METHOD=IMP EONLY=1 PRINT=1 NITER=5 ISAMPLE=1000 MAPITER=0
I've got EPS : 0.00064 (RSE=63%)
but
$EST METHOD=SAEM INTERACTION NBURN=3000 NITER=500 AUTO=1 PRINT=100
SEED=123235489
$EST METHOD=IMP EONLY=1 PRINT=1 NITER=5 ISAMPLE=1000 MAPITER=0
I've got EPS : 0.0223 (RSE=18%)
Could i trust on the good results (EPS=0.0223)? How can we control this
problem?
Thank you very much,
Hai, LE Ba
Ph.D Student
La faculté de Pharmacie - Aix Marseille université
Hanoi university of Pharmacy
Email: [email protected]
[email protected] <[email protected]>;
[email protected]