RE: Using evid 0 before dosing

From: Bill Denney Date: November 06, 2019 technical Source: mail-archive.com
Hi Carlos, It is commonly used. For most datasets, there will be at least one observation that occurs before dosing to estimate the baseline value, and in almost every scenario, the modeling dataset should mirror the real world actions. So, there is no issue with it, and usually you will have an EVID=0 before the first dose. Thanks, Bill
Quoted reply history
-----Original Message----- From: [email protected] <[email protected]> On Behalf Of Carlos ST Sent: Wednesday, November 6, 2019 10:03 AM To: [email protected] Subject: [NMusers] Using evid 0 before dosing Dear NMUsers, I would like advice in the best practice to use evid 0 before dosing, which is to say an observation just before a dosing (*to estimate the value in that compartment just before dosing event). Thank you, Carlos,
Nov 06, 2019 Carlos ST Using evid 0 before dosing
Nov 06, 2019 Bill Denney RE: Using evid 0 before dosing
Nov 06, 2019 Rob ter Heine RE: Using evid 0 before dosing
Nov 06, 2019 Dennis Fisher Re: Using evid 0 before dosing
Nov 06, 2019 Rob ter Heine RE: Using evid 0 before dosing
Nov 06, 2019 Paolo Denti Re: Using evid 0 before dosing
Nov 06, 2019 Mark Sale Re: Using evid 0 before dosing
Nov 06, 2019 Stephen Duffull RE: Using evid 0 before dosing