Re: cumulative AUC
Hi Sam,
Can't you simply dose with evid=4 (reset) into your auc compartment
(cmt=4)?
Op vr 8 nov. 2019 19:09 schreef Sam Liao <[email protected]>:
> Dear nmusers,
>
> I have a question how to reset cumulative AUC in a $DES model, where
> DADT(4) is set up as cumulative AUC of C1.
>
> Because the study is a four way crossover study, the cumulative value of
> A(4) need to rest to zero before each subsequent treatments.
>
> However, NONMEM do not allow setting A(4) to zero in the statement of
> control stream.
>
> Is there any work around of this problem?
>
> Best regards,
>
> Sam Liao
Quoted reply history
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