RE: Objective function
Sebastien:
All methods in NONMEM are -2LL based.
Robert J. Bauer, Ph.D.
Pharmacometrics R&D
ICON Early Phase
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Suite 100
Gaithersburg, MD 20878
Office: (215) 616-6428
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Quoted reply history
-----Original Message-----
From: [email protected] [mailto:[email protected]] On
Behalf Of sbihorel
Sent: Monday, January 16, 2017 3:13 AM
To: [email protected]
Subject: [NMusers] Objective function
Hi,
This might appear like a very naive question but I could not find the
information in the NONMEM use guide: what is the value of the objective
function for ITS, IMP, SAEM, and BAYES estimation methods in relation to the
log likelihood? Is it the standard minus 2 times the log likelihood like for
FO, FOCE, FOCEI, or LAPLACE methods?
Thank you
Sebastien