RE: Implementation of the OMEGA covariance matrix
Dear Ana,
If you only want to consider covariance between 3 parameters, I suggest you put
these three in an $OMEGA BLOCK(3) and list the remaining OMEGAs separately
outside the block.
Best,
Elke
Quoted reply history
-----Original Message-----
From: [email protected] [mailto:[email protected]] On
Behalf Of Ana Miranda Bastos
Sent: Tuesday, July 28, 2015 2:52 PM
To: [email protected]
Subject: [NMusers] Implementation of the OMEGA covariance matrix
Dear NMusers,
I wonder if someone could help me to implement the OMEGA covariance matrix
below.
$OMEGA
0.09 ; PPV_VMAX
0.00 0.09 ; PPV_V1
0.00 0.00 0.09 ; PPV_V2
0.00 0.00 0.00 0.09 ; PPV_KD
0.00 0.01 0.00 0.00 0.09 ; PPV_BMAX
0.00 0.01 0.00 0.00 0.01 0.09 ; PPV KM
I don't want to fix any value to zero, but I don't know how to better
illustrate that I would like to consider a covariance between:
. V1 and Bmax
. Bmax and Km
. V1 and Km
Any advice is highly appreciated. Thank you in advance.
Kind regards,
Ana
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Ana Bastos, Pharm, MSc, PhD student
Pharmacologie cellulaire et moléculaire
(Cellular and Molecular Pharmacology Unit)
Louvain Drug Research Institute
Université catholique de Louvain (Catholic University of Louvain)
UCL 7370 avenue E. Mounier 73
1200 Bruxelles, Belgique
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http://www.facm.ucl.ac.be