Re: Simulo: a new service for drug trial simulation

From: Leonid Gibiansky Date: June 23, 2015 technical Source: mail-archive.com
Actually, nonmem can be used to simulate the response-based dose adaptation without iteratively rerunning your model, with single simulation (using $ABB COMRES functionality to pass simulated response to the dose-adjustment algorithm code), although it is indeed cumbersome Leonid -------------------------------------- Leonid Gibiansky, Ph.D. President, QuantPharm LLC web: www.quantpharm.com e-mail: LGibiansky at quantpharm.com tel: (301) 767 5566
Quoted reply history
On 6/23/2015 4:48 AM, Faelens, Ruben (Belgium) wrote: > Dear NONMEM users, > > We all know how difficult it is to simulate full drug trials using > NONMEM. It is often necessary to generate the full dosing scheme(s) > beforehand, and response-based dose adaptation requires iteratively > rerunning your model until you have the results you are happy with. > > At SGS Exprimo, we have been working for 4 years to develop a new > software that makes drug trial simulation much more straight-forward. > The software has been developed in collaboration with Roche and has been > used internally within SGS Exprimo for the last 2 years. We are now > presenting it to the public as a new consultancy service. You may have > seen us in Crete at PAGE 2015. > > We invite you to visit our website www.simulo.eu http://www.simulo.eu > or contact us directly to request an on-site demo or web conference, or > to ask any questions you may have. > > We look forward to hearing from you. > > Kind regards, > > Ruben Faelens for SGS Exprimo > > *Ruben Faelens, MSc* > *Life Science Services - Exprimo* > IT Scientist > > Phone: > > +32 494 06 72 59 > > E-mail: > > [email protected] <mailto:[email protected]>_ > > Web: > > www.exprimo.com http://www.exprimo.com/ > > Information in this email and any attachments is confidential and > intended solely for the use of the individual(s) to whom it is addressed > or otherwise directed. Please note that any views or opinions presented > in this email are solely those of the author and do not necessarily > represent those of the Company. Finally, the recipient should check this > email and any attachments for the presence of viruses. The Company > accepts no liability for any damage caused by any virus transmitted by > this email. All SGS services are rendered in accordance with the > applicable SGS conditions of service available on request and accessible > at http://www.sgs.com/en/Terms-and-Conditions.aspx
Jun 23, 2015 Ruben Faelens Simulo: a new service for drug trial simulation
Jun 23, 2015 Leonid Gibiansky Re: Simulo: a new service for drug trial simulation
Jun 23, 2015 Mats Karlsson RE: Simulo: a new service for drug trial simulation
Jun 23, 2015 Michael Fossler RE: Simulo: a new service for drug trial simulation