Re: Simulo: a new service for drug trial simulation
Actually, nonmem can be used to simulate the response-based dose adaptation without iteratively rerunning your model, with single simulation (using $ABB COMRES functionality to pass simulated response to the dose-adjustment algorithm code), although it is indeed cumbersome
Leonid
--------------------------------------
Leonid Gibiansky, Ph.D.
President, QuantPharm LLC
web: www.quantpharm.com
e-mail: LGibiansky at quantpharm.com
tel: (301) 767 5566
Quoted reply history
On 6/23/2015 4:48 AM, Faelens, Ruben (Belgium) wrote:
> Dear NONMEM users,
>
> We all know how difficult it is to simulate full drug trials using
> NONMEM. It is often necessary to generate the full dosing scheme(s)
> beforehand, and response-based dose adaptation requires iteratively
> rerunning your model until you have the results you are happy with.
>
> At SGS Exprimo, we have been working for 4 years to develop a new
> software that makes drug trial simulation much more straight-forward.
> The software has been developed in collaboration with Roche and has been
> used internally within SGS Exprimo for the last 2 years. We are now
> presenting it to the public as a new consultancy service. You may have
> seen us in Crete at PAGE 2015.
>
> We invite you to visit our website www.simulo.eu http://www.simulo.eu
> or contact us directly to request an on-site demo or web conference, or
> to ask any questions you may have.
>
> We look forward to hearing from you.
>
> Kind regards,
>
> Ruben Faelens for SGS Exprimo
>
> *Ruben Faelens, MSc*
> *Life Science Services - Exprimo*
> IT Scientist
>
> Phone:
>
> +32 494 06 72 59
>
> E-mail:
>
> [email protected] <mailto:[email protected]>_
>
> Web:
>
> www.exprimo.com http://www.exprimo.com/
>
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