Workshop on Quantitative Methods in Pharmacology: Introduction to Pharmacometrics

Still some places available for the: Workshop on Quantitative Methods in Pharmacology: Introduction to Pharmacometrics March 24-26, 2014: The Carolina Inn on the Campus of the University of North Carolina at Chapel Hill, NC This is a 3-day course designed to help scientists to understand and use fundamental pharmacometrics concepts for increasing efficiency in drug discovery and development. The workshop includes lectures and hands-on training on concepts, applications, and software tools for pharmacometrics. A Clinical Trial Simulator developed in R will be used to illustrate the use of R in a pharmacometrics framework including the population PK and PK/PD concepts, inter and intra subject variability and the impact of covariates on the clinical trial outcomes. As a working example, the simulator will be used to generate data of a virtual clinical trial in non-small cell lung cancer. The model will include a semi-mechanistic PK/PD tumor growth component, the link between PK and adverse events and the link between tumor growth and survival. The virtual data will then be used to illustrate the population analysis in NONMEM. The R scripts (including the trial simulator) and the NONMEM control streams used will be distributed to the participants. Additional details are available at: http://www.pharmacometricaworkshop.webs.com www.pharmacometricaworkshop.webs.com Roberto Gomeni, PhD, HDR, Adjunct Professor at UNC PharmacoMetrica Longcol, 12270 La Fouillade (France) E-mail: <mailto:[email protected]> [email protected] http://www.pharmacometrica.com/ www.pharmacometrica.com