IV and SC injection

From: Justus Bingham Date: October 17, 2013 technical Source: mail-archive.com
Hello, I would like to model some data for both IV and SC injection simultaneously to estimate F1. The first order absorption for SC does not fit well and I would like to try to fit with zero order absorption. I would like to know if this code is correct in order to do this. I have both IV and SC dosed in the dataset into CMT =1 for IV RATE=0 for SC RATE= -2. Thanks, Justus $PK TVCL = THETA(1) TVV = THETA(2) TVDUR = THETA(3) CL = TVCL*EXP(ETA(1)) V = TVV*EXP(ETA(2)) D1 = TVDUR*EXP(ETA(3)) F1= THETA(4)
Oct 17, 2013 Justus Bingham IV and SC injection
Oct 17, 2013 Leonid Gibiansky Re: IV and SC injection