Second Workshop on Pharmacometrics

Final call: Second Workshop on Pharmacometrics, a tool for optimizing drug development, Château de Longcol, La Fouillade (France), May 13-16, 2013: http://www.pharmacometrica.webs.com The workshop is intended for scientists in the pharmaceutical industry, regulatory agencies, contract research organizations, and academia who are expected to implement and apply model-based approach and to deploy innovative pharmacometrics concepts and strategies for better supporting and increasing the efficiency of drug development. A Clinical Trial Simulator developed in R will be used to illustrate the use of R in pharmacometrics, the population PK and PK/PD concepts, the relevance of the inter and intra subject variability and the impact of covariates on the clinical trial outcomes. As a working example, the simulator will be used to generate data of a virtual clinical trial in non-small cell lung cancer. The model will include a semi-mechanistic PK/PD tumor growth component, the link between PK and adverse events and the link between tumor growth and survival. The simulated virtual data will then be used in a population analysis in NONMEM. The R scripts (including the trial simulator) and the NONMEM control streams used will be distributed to the participants. For more information about the course, including the daily schedule, please visit the workshop website: http://www.pharmacometrica.webs.com Workshop venue: Château de Longcol (France): www.chateaudelongcol.com Roberto Gomeni, PhD HDR PharmacoMetrica Longcol, 12270 La Fouillade (France) E-mail: [email protected] Mobile: +33(0) 760 45 1976 Fax: +33 (0) 983 23 3188 www.pharmacometrica.com