modeling of total concentration of two drugs with different kinetics in NONMEM
Dear All,
I'm trying to model in NONMEM the kinetics of two drug entities co-existing in
the blood. Since the assay cannot differentiate these two entities, I only have
the total concentration of these two in the blood. Does anyone has similar
experience? Can you please share the NONMEM code?
Thanks,
Yaming
Yaming Hang, Ph.D.
Pharmacometrics
Biogen Idec
14 Cambridge Center
Cambridge, MA 02142
Office: 781-464-1741
Fax: 617-679-3463
Email: [email protected]<mailto:[email protected]>