Guidelines for a fresh modeller
Dear NONMEMusers
I am working with my very first pop-PK model with NONMEM and have no
experience. I have read a lot of theory but lack experience of actually
using nonmem. I see the OFV and estimates, but have trouble knowing how to
interpret the results and the graphs, and how to improve the structural
model before incorporate covariates. When I have nothing to compare with,
it is difficult to know if I have found the right structural model and
whether my results are actually good or bad. I also wonder what kind of
plots in the plot jungle which you experience modelers find most useful to
look at when trying to improve a model, and how you know which starting
estimates to choose.
Maybe any of you remember how it was to be a fresh modeller, and remember
what you did to get your first experience. I could use a good, pedagogical,
stepwise guide on modelling, with some illustrative examples and excercises
to practice with before starting on my own dataset. Do any of you know if
this is available?
Thanks in advance :)