Re: Estimation method selection

From: Paul Matthias Diderichsen Date: October 17, 2011 technical Source: mail-archive.com
On 10/9/2011 2:01 PM, tausif Ahmed wrote: > 1. When we tried diff. estimation methods in nm 7.1 such as FO, FOCE > or laplace. We got lowest OFV with laplace. Can we select the > estimation method based on only OFV. We got the estimates in both FO > and laplace but variability was reaching the boundary in case of FO. When I went to a training course in NONMEM 7, a prominent developer told us that "FO can F.O.". I found that quite amusing, and I believe that I have never used FO since... -- Paul Matthias Diderichsen, PhD Quantitative Solutions B.V. +31 624 330 706
Oct 10, 2011 Tausif Ahmed Estimation method selection
Oct 17, 2011 Paul Matthias Diderichsen Re: Estimation method selection
Oct 17, 2011 Martin Bergstrand RE: Estimation method selection