FW: can NONMEM/gfortran be used on a 64bit dell workstation with Windows 7?

Hello.exe is just a minimal test of the compiler, not sufficient to insure proper operation of the compiler. However, we have had no difficulty installing NONMEM 7.2 on 64-bit Windows 7 using the compiler found on the NONMEM distribution CD (gfortran-windows-460.exe). No LIBRARY variable is set (or needed) for this version. We have seen issues related to co-installation of gfortran and g95 (and gfortran finding and trying to use the g95 libraries). The two compilers can be made to co-exist, but, I don't recommend it. The main issue has been assuring that User Access Control for Windows 7 is turned off before installation. The following is output from a successful install on said system: Microsoft Windows [Version 6.1.7601] Copyright (c) 2009 Microsoft Corporation. All rights reserved. C:\Users\Bill>gfortran --version GNU Fortran (GCC) 4.6.0 20100620 (experimental) [trunk revision 161045] Copyright (C) 2010 Free Software Foundation, Inc. GNU Fortran comes with NO WARRANTY, to the extent permitted by law. You may redistribute copies of GNU Fortran under the terms of the GNU General Public License. For more information about these matters, see the file named COPYING C:\Users\Bill>ar -V GNU ar (GNU Binutils) 2.20.51.20100613 Copyright 2010 Free Software Foundation, Inc. This program is free software; you may redistribute it under the terms of the GNU General Public License version 3 or (at your option) any later version. This program has absolutely no warranty. C:\Users\Bill>e: E:\>SETUP72 e: c:\nm72gf gfortran y ar NONMEM 7.2.0 INSTALLATION UTILITY - Windows/DOS batch file version For instructions, see readme_7.2.0.pdf or readme_7.2.0.txt on the CD SETUP72 e: c:\nm72gf gfortran y ar same rec i unzip.exe nonmem72e.zip nonmem72r.zip CD-ROM drive is e: NONMEM 7.2.0 directory is c:\nm72gf Command for FORTRAN compiles is gfortran Optimization for Fortran compiles is y Command to build NONMEM archive is ar Sizes is same Recompile is rec All binaries will be recompiled Interactive is i Unzip is unzip.exe Encrypted source file is nonmem72e.zip Unencrypted file is nonmem72r.zip To learn how to override the defaults, enter SETUP72 help Continue (y/n)? [y] The directory c:\nm72gf does not exist. Step 1. Creating c:\nm72gf Step 1a. Copy files from e: to c:\nm72gf 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. 1 file(s) copied. Step 1b. Copy files from e:\NONMEM_7.2.0 to c:\nm72gf Installing NONMEM 7.2.0 (Enter Ctrl-C to interrupt) ... Step 2a. Make sub-directories of c:\nm72gf Extract rest of files Using resource\SIZES.f90 Choosing platform-dependent files ... Will use install_Win.exe Will use util\finish_win_gfortran.bat ===Checking compiler start compile/link end compile/link === Copying NONMEM license file nonmem.lic to c:\nm72gf\license\nonmem.lic Warning: the license may be expired or may expire soon. When this happens, NONMEM runs will fail. If you have a new license file from IDS, you may stop, replace it and restart SETUP72. Otherwise, allow NONMEM installation to finish at this time. Obtain a new license file from IDS ([email protected]) as soon as possible and replace c:\nm72gf\license\nonmem.lic Changes to License file, resource\SIZES.f90 and other resource files may be made here. Continue (y/n)? [y] Step 6. Compile resource files Compile of resource files was successful. ar: creating resource.a resource directory has been compiled Continue (y/n)? [y] Step 9. Compile all remaining source files This will take a long time. See file c:\nm72gf\progress.txt for compiler progress Step 10. Build NONMEM archive nm\nonmem.a Step 13. Create shell script util\nmfe72 Step 14. Create directory run run contains the following files: nmfe72.bat CONTROL3 CONTROL5 DATA3 THEOPP REPORT5IDS.txt run contains additional files Installation of NONMEM 7.2.0 is finished. For future reference, the command has been saved in file SETUP.TXT Please review c:\nm72gf\compilemsgs.txt c:\nm72gf\finishmsgs.txt Ignore warnings. Report error messages. Do you want to install help and html files and Users Guides? Continue (y/n)? [y] Help and html files and Users Guides will be installed. Step 15. Install NONMEM Users Guide files in c:\nm72gf\guides Unzipping guides.zip... To use the NONMEM Users Guides, open pdf files in c:\nm72gf\guides using Adobe Reader. Step 16. Install On-line help files in c:\nm72gf\help Unzipping help.zip... "Installing On-Line Help Tools ..." For online help, enter (e.g.) cd c:\nm72gf\help nmhelp advan2 Step 17. Install HTML files in c:\nm72gf\html (this may take a while) ... Unzipping html.zip... For online help HTML files, open c:\nm72gf\html\index.htm in web browser Do you want to test the installation? Continue (y/n)? [y] Testing the installation. Commands are cd c:\nm72gf\run nmfe72 CONTROL5 REPORT5.txt -prdefault If the run is successful, file REPORT5.txt will be created. doing nmtran WARNINGS AND ERRORS (IF ANY) FOR PROBLEM 1 (WARNING 2) NM-TRAN INFERS THAT THE DATA ARE POPULATION. (WARNING 43) THE $PK BLOCK REQUESTS "CALL ONCE PER INDIVIDUAL RECORD", BUT DATA ITEMS ARE USED IN THE $PK BLOCK. VALUES OF THESE DATA ITEMS SUBSEQUENT TO THOSE FROM THE FIRST EVENT RECORD WILL BE IGNORED. IF THIS IS NOT APPROPRIATE, THE CALL DATA ITEM CAN BE USED TO OBTAIN ADDITIONAL CALLS, OR $PK'S CALLING PROTOCOL SHOULD BE CHANGED. CREATING MUMODEL ROUTINE... 1 file(s) copied. Finished compiling fsubs Completed call to gfcompile.bat Starting nonmem execution ... License Registered to: Temporary License File for Installation Expiration Date: 31 JUL 2011 Current Date: 19 MAY 2011 Days until program expires : 72 First Order MONITORING OF SEARCH: 0ITERATION NO.: 0 OBJECTIVE VALUE: 110.244034784025 NO. OF FUNC. EVALS.: 6 CUMULATIVE NO. OF FUNC. EVALS.: 6 NPARAMETR: 3.0000E+00 8.0000E-02 4.0000E-02 6.0000E+00 5.0000E-03 3.0000E-01 2.0000E-04 6.0000E-03 4.0000E-01 4.0000E-0 1 PARAMETER: 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-01 1.0000E-0 1 GRADIENT: 1.4640E+01 -1.6691E+01 5.6460E+01 -9.4129E+00 -1.1699E+01 1.0623E+01 -6.3485E-01 -4.7803E+01 -9.6457E+00 5.2414E+0 0 0ITERATION NO.: 5 OBJECTIVE VALUE: 105.453694508227 NO. OF FUNC. EVALS.: 7 CUMULATIVE NO. OF FUNC. EVALS.: 45 NPARAMETR: 2.8166E+00 8.0433E-02 3.8563E-02 6.6123E+00 9.7862E-03 -3.9509E-02 2.3438E-04 8.1375E-03 4.9657E-01 4.0346E-0 1 PARAMETER: -5.3055E-02 1.0703E-01 5.7598E-02 1.4858E-01 1.8644E-01 -1.2545E-02 1.5794E-01 1.3452E-01 3.7714E-02 1.0431E-0 1 GRADIENT: 3.5103E-01 -1.3214E+01 2.8003E+01 1.1115E+00 1.9193E+00 -5.3252E+00 7.1533E-02 -2.2091E+01 -1.4424E+00 8.2329E+0 0 0ITERATION NO.: 10 OBJECTIVE VALUE: 104.747695563240 NO. OF FUNC. EVALS.: 7 CUMULATIVE NO. OF FUNC. EVALS.: 80 NPARAMETR: 2.7362E+00 7.6935E-02 3.5982E-02 5.7362E+00 1.0840E-03 -2.9208E-01 2.3701E-04 9.4013E-03 5.1805E-01 3.8850E-0 1 PARAMETER: -1.1928E-01 4.9234E-02 -2.3022E-02 7.7517E-02 2.2174E-02 -9.9574E-02 1.9498E-01 1.4956E-01 -1.7173E-01 8.5414E-0 2 GRADIENT: -1.3933E+00 -7.4632E+00 9.3144E+00 1.0280E+00 9.6395E-01 -3.1313E+00 1.0212E+00 -5.3784E+00 -2.0828E+00 -9.1477E-0 1 0ITERATION NO.: 15 OBJECTIVE VALUE: 104.561086502415 NO. OF FUNC. EVALS.: 7 CUMULATIVE NO. OF FUNC. EVALS.: 116 NPARAMETR: 2.7735E+00 7.8097E-02 3.6292E-02 5.5466E+00 5.1735E-03 -1.2911E-01 2.3941E-04 9.0947E-03 5.1461E-01 3.8752E-0 1 PARAMETER: -8.8567E-02 6.8686E-02 -1.2994E-02 6.0711E-02 1.0762E-01 -4.4762E-02 1.9028E-01 1.4643E-01 -8.4016E-02 8.4157E-0 2 GRADIENT: 7.7937E-03 5.7190E-03 3.0426E-02 -5.1648E-03 -1.2939E-02 1.4490E-02 7.4602E-04 -2.5227E-02 -3.1443E-03 1.5799E-0 2 0ITERATION NO.: 19 OBJECTIVE VALUE: 104.561067398632 NO. OF FUNC. EVALS.: 0 CUMULATIVE NO. OF FUNC. EVALS.: 149 NPARAMETR: 2.7739E+00 7.8129E-02 3.6307E-02 5.5498E+00 5.2393E-03 -1.2767E-01 2.3985E-04 9.1064E-03 5.1521E-01 3.8750E-0 1 PARAMETER: -8.8304E-02 6.9219E-02 -1.2510E-02 6.0998E-02 1.0895E-01 -4.4249E-02 1.9095E-01 1.4652E-01 -8.3269E-02 8.4127E-0 2 GRADIENT: 1.2144E-04 -1.4882E-04 -6.6255E-06 -7.5745E-05 -1.6157E-05 1.1307E-04 6.4128E-05 1.1193E-04 -1.7655E-05 4.2674E-0 5 Elapsed estimation time in seconds: 0.11 Elapsed covariance time in seconds: 0.02 You should now compare REPORT5.txt vs. REPORT5IDS.txt Values should be similar. E.g., the following should be identical: find "#OBJV:" REPORT5.txt ---------- REPORT5.TXT #OBJV:******************************************** 104.561 ************************************************** find "#OBJV:" REPORT5IDS.txt ---------- REPORT5IDS.TXT #OBJV:******************************************** 104.561 ************************************************** c:\nm72gf>