Negative OFV number

From: Yuhong Chen Date: December 17, 2010 technical Source: mail-archive.com
Dear All, I am reviewing a PopPK report, and found the OFV is negative. The model used the log transformed data. Is it can be the reason of negative OFV number? Is the negative OFV number means the model may have problem? Any suggestion will be greatly appreciated. Warm regards, Yuhong
Dec 17, 2010 Yuhong Chen Negative OFV number
Dec 18, 2010 Serge Guzy RE: Negative OFV number
Dec 19, 2010 Kenneth Kowalski RE: Negative OFV number