An Exciting Modelling & Simulation Position at GSK

Due to the unwavering commitment of GlaxoSmithKline (GSK) to model-based approaches in drug development, we are looking for a talented and motivated individual for an exciting position in the department of Clinical Pharmacology Modelling & Simulation (CPMS). The position will be based at our modern facilities in Stevenage, just outside London, UK. By conducting mathematical and statistical modelling to understand disease and drug characteristics and performing computer simulation to optimise trial design, we integrate all existing data, both internal and in public domain, to enhance the quality and efficiency of knowledge generation and decision making. We provide crucial input to the design and implementation of clinical plans for compounds at all development stages, from prior to first in human to after regulatory approval. We play a key role in the design and interpretation of clinical studies to inform business decisions at critical milestones such as first in human, proof of concept, dose ranging and pivotal trials. We also write essential sections of regulatory submission documents and product prescribing information. Our ultimate remits are to assess the risks associated with the assets and their development programs, to identify the optimal dose on balance of efficacy and safety, and to assist commercial differentiation of our products. Publication and presentation at scientific conferences are strongly encouraged to publicise our work and to contribute to the advancement of the science and methodology of quantitative approaches in drug development. A doctorate degree, or equivalent, in a relevant field such as pharmacokinetics, pharmacology, statistics or engineering is required. So is demonstrated knowledge in clinical pharmacology principles and experience in modelling and simulation methodologies. Good communication skills are essential for effectively influencing internal and external decision makers. A collaborative mindset is necessary for successful partnership with both internal scientists (such as biologists, statisticians and clinicians) and external consultants. At GSK, we promote and reward high performance through innovation. As a member of the global CPMS team, you'll have the challenges and opportunities of exploring, learning and utilising state-of-the-art methodologies to enhance the quality and efficiency of drug development. We also offer highly competitive benefits and compensation packages that are designed to attract and retain the very best. If you are interested in this position, please visit http://www.gsk.com/careers quoting Req. ID 60416. Should you require more information about the role, please contact Chao Chen: [email protected]<mailto:[email protected]>. ----------------------------------------------------------- This e-mail was sent by GlaxoSmithKline Services Unlimited (registered in England and Wales No. 1047315), which is a member of the GlaxoSmithKline group of companies. The registered address of GlaxoSmithKline Services Unlimited is 980 Great West Road, Brentford, Middlesex TW8 9GS.