multiple problems in a control file

Hi, I'm trying to run multiple single-subject problems within a single control file but there is something I'm not doing right because when I include the $SUBROUTINE LIBRARY option, then NONMEM won't estimate the model parameters. However if I omit that option, I can't run the second problem. I pasted my test control file below . $PROB RUN# 001 $INPUT C ID SUBJ AMT RATE EVID DAY DAT1=DROP TAD TIME DV MDV $DATA TESTDATA.CSV RECS=ID IGNORE=C LAST20=50 $SUBROUTINES ADVAN2 TRANS1 SUBROUTINE=LIBRARY $PK K=THETA(1) V=THETA(2) KA=THETA(3) S2=V $ERROR Y = F + F*ERR(1) IPRED=F $EST PRINT=5 MAX=9999 SIG=3 $THETA (0,0.5,);[K] (0,3000,);[V] (0, 1.3);[KA] $OMEGA 0.1 ;[P] $PROB RUN# 002 $INPUT C ID SUBJ AMT RATE EVID DAY DAT1=DROP TAD TIME DV MDV $DATA TESTDATA.CSV RECS=ID NOREWIND IGNORE=C LAST20=50 $PK K=THETA(1) V=THETA(2) KA=THETA(3) S2=V $ERROR Y = F + F*ERR(1) IPRED=F $EST PRINT=5 MAX=9999 SIG=3 $THETA (0,0.5,);[K] (0,3000,);[V] (0, 1.3);[KA] $OMEGA 0.1 ;[P] I'd really appreciate if somenone could point me in the right direction with this. Tx :o) Pierre-Olivier ----------------------------------------- Ce courriel et toutes ses pièces jointes sont confidentiels et ne peuvent être utilisés que par le destinataire ou l'organisation à qui ils sont adressés. Si vous n'êtes pas le destinataire visé, veuillez en informer l'expéditeur et supprimez immédiatement le courriel. Ce message confirme également que ce courriel et ses pièces jointes ont été inspectés par notre logiciel d'antivirus pour votre sécurité. ----------------------------------------- This e-mail and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the sender and delete it immediately. This footnote also confirms that this e-mail message and its attached file(s) have been swept for your security by our antivirus software using the latest virus signatures. Anapharm Par Proofpoint