multiple problems in a control file

Hi, I'm trying to run multiple single-subject problems within a single control file but there is something I'm not doing right because when I include the $SUBROUTINE LIBRARY option, then NONMEM won't estimate the model parameters. However if I omit that option, I can't run the second problem. I pasted my test control file below . $PROB RUN# 001 $INPUT C ID SUBJ AMT RATE EVID DAY DAT1=DROP TAD TIME DV MDV $DATA TESTDATA.CSV RECS=ID IGNORE=C LAST20P $SUBROUTINES ADVAN2 TRANS1 SUBROUTINE=LIBRARY $PK K=THETA(1) V=THETA(2) KA=THETA(3) S2=V $ERROR Y = F + F*ERR(1) IPRED=F $EST PRINT=5 MAX99 SIG=3 $THETA (0,0.5,);[K] (0,3000,);[V] (0, 1.3);[KA] $OMEGA 0.1 ;[P] $PROB RUN# 002 $INPUT C ID SUBJ AMT RATE EVID DAY DAT1=DROP TAD TIME DV MDV $DATA TESTDATA.CSV RECS=ID NOREWIND IGNORE=C LAST20P $PK K=THETA(1) V=THETA(2) KA=THETA(3) S2=V $ERROR Y = F + F*ERR(1) IPRED=F $EST PRINT=5 MAX99 SIG=3 $THETA (0,0.5,);[K] (0,3000,);[V] (0, 1.3);[KA] $OMEGA 0.1 ;[P] I'd really appreciate if somenone could point me in the right direction with this. Tx :o) Pierre-Olivier ----------------------------------------- Ce courriel et toutes ses pices jointes sont confidentiels et ne peuvent tre utiliss que par le destinataire ou l'organisation qui ils sont adresss. Si vous n'tes pas le destinataire vis, veuillez en informer l'expditeur et supprimez immdiatement le courriel. Ce message confirme galement que ce courriel et ses pices jointes ont t inspects par notre logiciel d'antivirus pour votre scurit. ----------------------------------------- This e-mail and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the sender and delete it immediately. This footnote also confirms that this e-mail message and its attached file(s) have been swept for your security by our antivirus software using the latest virus signatures. Anapharm Par Proofpoint