RE: unbalanced design
Linear Mixed Models for Longitudinal Data by Geert Verbeke
http://www.amazon.com/exec/obidos/search-handle-url/102-2006236-4753744
?%5Fencoding=UTF8&search-type=ss&index=books&field-author=Geert%20Verbek
e , Geert Molenberghs
http://www.amazon.com/exec/obidos/search-handle-url/102-2006236-4753744
?%5Fencoding=UTF8&search-type=ss&index=books&field-author=Geert%20Molenb
erghs
Yaning Wang, Ph.D.
Team Leader, Pharmacometrics
Office of Clinical Pharmacology
Office of Translational Science
Center for Drug Evaluation and Research
U.S. Food and Drug Administration
Phone: 301-796-1624
Email: [EMAIL PROTECTED]
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________________________________
From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED]
On Behalf Of Mark Sale - Next Level Solutions
Sent: Tuesday, September 02, 2008 1:28 PM
To: [email protected]
Subject: [NMusers] unbalanced design
Does anyone have a reference to a publication assessing whether
mixed effect modeling (NONMEM in particular) is robust for unbalances
studies? I see if in a number of courses (including the original
beginners course for NONMEM), but can't find a publication.
thanks
Mark Sale MD
Next Level Solutions, LLC
www.NextLevelSolns.com
919-846-9185
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