Re: NONMEM memory vs. run time

The increase in memory consumption doesn't impact runtime positively or negatively, unless of course your system doesn't have enough physical memory to accommodate the increase. NONMEM's memory footprint is directly related to the buffer values in the SIZES file, as you increase the values the memory footprint increases to accommodate. In the end processor speed is really the only thing that positively or negatively effects NONMEM runtime. Leonid Gibiansky wrote: > Dear All, > I noticed that the Nonmem installed with NMQUAL "big nm6" defaults > instead of the standard ones results in approximately 10-times increase > in the memory required to run Nonmem (on my recent problem, from 12 MB > to 140 MB). I am wondering whether anybody checked how this influences > the run time. Is it better (in terms of the run time) to use standard > sizes, or "big" is OK if you have enough RAM? > Thanks! > Leonid -- Darin Perusich Unix Systems Administrator Cognigen Corporation 395 Youngs Rd. Williamsville, NY 14221 Phone: 716-633-3463 Email: [EMAIL PROTECTED]