RE: Simultaneous PK and Cell Life Span PD modeling
Mark:
Thanks for your suggestions! I have removed "DEFOBS"
from CMT6, and it is now running.
Toufigh:
Yes, I do have dense PK and PD data for this modeling
exercise. I presented the simultaneous PK/PD modeling
results at last month's AAPS NBC as a poster. I am now
attempting to use the cell life span model to see if
there any improvements in model fitting. Note that
this is an mAb which reduces the NK cell count in the
peripheral blood.
Thanks!
Wei-jian
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