AUC and segmented post treatment exposure
Dear all,
I am working with a population model of 100 patients sparsely sampled for 60
days. It is a 2-compartment model with first order absorption and repeated
oral administration for 3 days. I have some difficulties in finding a code for
estimating AUC for these patients so if anyone could help me that would save me
a lot of time.
How do I code for AUC in repeated oral dosing for a 2-compartment model?
Is it possible to code for AUC segments (e.g. 0-20 days and/or 20-40 days after
administration)?
Thanks
/Joel Tarning
_____________________________________________
Joel Tärning, MSc, PhD-student
Göteborg University
Department of Pharmacology
P.O. Box 431
405 30 Göteborg
Phone: +46 (0) 31 773 3240
Cellular: +46 (0) 708 514849
Fax: +46 (0) 31 773 3284
e-mail: [EMAIL PROTECTED] (mailto:[EMAIL PROTECTED])