Re: RE: RE: What are the best studies to combine?
From: musor000@optonline.net
Subject: Re: RE: RE: [NMusers] What are the best studies to combine?
Date: Fri, 31 Mar 2006 07:12:38 -0500
Hello Mark,
I agree. Healthy vlunteers and diseased subjects have different demohraphics. Demographic parameters overlap,
but the differences are significant. Thus, we are in grey area. We may not be able to separate study effect
and effect of demographic variables completely. This should be an issue every time someone pools the data.
I assume there are few ways to deal with this:
1. Try to find similar studies;
2. Pool a lot of studies;
3. Compare pooled results and results by population (healthy vs diseased);
Thank you,
Pavel