RE: interoccasion variability

From: "SIMON Nicolas" nicolas.simon@mail.ap-hm.fr Subject: RE: [NMusers] interoccasion variability Date: Tue, 7 Feb 2006 10:18:59 +0100 What difference shall we make between IOC and inter-individual variability? In my point of view, IOC belongs to the difference of an individual PK parameters between i.e. monday and another day. Each PK profile is seen as a new occasion. Intra-individual variability is more global and also takes into account that an individual may have a PK parameter changing during one PK profile (i.e. due to biological rythms). Best regards, Nicolas SIMON Department of Clinical Pharmacology Medical School of Marseilles 27 Bd Jean Moulin F-13385 Marseilles _______________________________________________________